Gel 1100 Toothpaste with Nano-Hydroxyapatite

CariFree Gel 1100 combines four key technologies in a single formula: fluoride, nanoXIM® nano-hydroxyapatite, xylitol, and proprietary pH-support technology. Together, they support cavity protection, enamel health, and a healthier oral environment.

Nano-hydroxyapatite is a lab-created mineral that closely resembles the natural mineral structure found in tooth enamel. CariFree uses medical-grade nanoXIM® nano-hydroxyapatite from FLUIDINOVA, a trusted leader in nano-hydroxyapatite technology.

When oral pH drops, teeth become more vulnerable to acid challenges. CariFree products are designed to help support a healthier oral pH because cavity prevention starts long before a cavity is visible.

Yes. Gel 1100 is designed for daily use and is recommended for adults and children ages 2 and older when used as directed.

Yes. Gel 1100 features a mild, moisturizing gel formula that many people with dry mouth find comfortable for daily use.

RDA stands for Relative Dentin Abrasivity, a measure of how abrasive a toothpaste is.Gel 1100 has an RDA of 40, making it a low-abrasion toothpaste designed to clean effectively while remaining gentle on enamel.

They serve different roles and work well together. Fluoride supports cavity protection, while nano-hydroxyapatite supports enamel health. CariFree combines both in a single formula to provide a more complete approach to daily oral care.

Our focus isn’t on using the highest percentage possible. It’s using the highest-quality nano-hydroxyapatite available. While we don’t disclose exact formula percentages, we believe quality matters more than concentration alone.

Research suggests that particle size, shape, and stability all influence how nano-hydroxyapatite performs. That’s why CariFree has used nanoXIM® by FLUIDINOVA since 2012, a clinically studied, medical-grade nano-hydroxyapatite designed specifically for oral care.

The natural flavor used in Mint Gel 1100 is spearmint oil. We chose spearmint oil because it provides a clean, refreshing flavor that people enjoy using every day. Consistency is one of the most important factors in oral health, and taste plays a significant role in maintaining a daily brushing routine.

Some consumers have questions about essential oils and the oral microbiome. CariFree’s approach is to formulate products that support long-term oral health through pH management, fluoride, nano-hydroxyapatite, and xylitol. Spearmint oil is used primarily as a flavoring ingredient within the formula, helping create a brushing experience people enjoy and use consistently.

The formula has not changed. The Gel 1100 is both a cosmetic and OTC drug, to improve transparency for our customers, we chose to follow cosmetic labeling requirements 21 CFR § 701.3, “The label on each package of a cosmetic shall bear a declaration of the name of each ingredient in descending order of predominance…”

No, there are no animal-based ingredients in the CariFree products.

Our glycerin is derived from palm.

Our starch is made from corn.

Our natural flavoring in the mint Gel 1100 is spearmint oil.

Our silica is precipitated silicon dioxide (mineral).

Fluoride and nano-hydroxyapatite together create fluorapatite, which is more resistant to demineralization, a huge bonus when the goal is prevention.

Our xylitol is sourced from non-GMO corn. Xylitol is naturally found in many fruits and vegetables, and corn is one of the most common and sustainable commercial sources.